Thursday 13-Thursday Thirteen Frequent Side Effects of Chantix

t13-71

This list is from the Pfizer/Chantix web site.

Following is a list of treatment-emergent adverse events reported by patients treated with CHANTIX during all clinical trials. The listing does not include those events already listed in the previous tables or elsewhere in labeling, those events for which a drug cause was remote, those events which were so general as to be uninformative, and those events reported only once which did not have a substantial probability of being acutely life-threatening.

  1. GASTROINTESTINAL DISORDERS. Frequent: Diarrhea, Gingivitis. Infrequent: Dysphagia, Enterocolitis, Eructation, Gastritis, Gastrointestinal hemorrhage, Mouth ulceration, Esophagitis. Rare: Gastric ulcer, Intestinal obstruction, Pancreatitis acute.
  2. GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS. Frequent: Chest pain, Influenza like illness, Edema, Thirst. Infrequent: Chest discomfort, Chills, Pyrexia.
  3. INVESTIGATIONS. Frequent: Liver function test abnormal, Weight increased. Infrequent: Electrocardiogram abnormal, Muscle enzyme increased, Urine analysis abnormal.
  4. MUSCULOSKELETAL AND CONNECTIVE TISSUE DISORDERS. Frequent: Arthralgia, Back pain, Muscle cramp, Musculoskeletal pain, Myalgia. Infrequent: Arthritis, Osteoporosis. Rare: Myositis.
  5. NERVOUS SYSTEM DISORDERS. Frequent: Disturbance in attention, Dizziness, Sensory disturbance. Infrequent: Amnesia, Migraine, Parosmia, Psychomotor hyperactivity, Restless legs syndrome, Syncope, Tremor. Rare: Balance disorder, Cerebrovascular accident, Convulsion, Dysarthria, Facial palsy, Mental impairment, Multiple sclerosis, Nystagmus, Psychomotor skills impaired, Transient ischemic attack, Visual field defect.
  6. PSYCHIATRIC DISORDERS. Frequent: Anxiety, Depression, Emotional disorder, Irritability, Restlessness. Infrequent: Aggression, Agitation, Disorientation, Dissociation, Libido decreased, Mood swings, Thinking abnormal. Rare: Bradyphrenia, Euphoric mood, Hallucination, Psychotic disorder, Suicidal ideation.
  7. RENAL AND URINARY DISORDERS. Frequent: Polyuria. Infrequent: Nephrolithiasis, Nocturia, Urine abnormality, Urethral syndrome. Rare: Renal failure acute, Urinary retention.
  8. REPRODUCTIVE SYSTEM AND BREAST DISORDERS. Frequent: Menstrual disorder. Infrequent: Erectile dysfunction. Rare: Sexual dysfunction.
  9. RESPIRATORY, THORACIC AND MEDIASTINAL DISORDERS. Frequent: Epistaxis, Respiratory disorders. Infrequent: Asthma. Rare: Pleurisy, Pulmonary embolism.
  10. SKIN AND SUBCUTANEOUS TISSUE DISORDERS. Frequent: Hyperhidrosis. Infrequent: Acne, Dermatitis, Dry skin, Eczema, Erythema, Psoriasis, Urticaria. Rare: Photosensitivity reaction.
  11. VASCULAR DISORDERS. Frequent: Hot flush, Hypertension. Infrequent: Hypotension, Peripheral ischemia, Thrombosis.

Post-Marketing Experience:
12. The following adverse events have been reported during post-approval use of Chantix. Because these events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

13. There have been reports of depressed mood, agitation, changes in behavior, suicidal ideation and suicide in patients attempting to quit smoking while taking Chantix. Smoking cessation with or without treatment is associated with nicotine withdrawal symptoms and the exacerbation of underlying psychiatric illness. Not all patients had known pre-existing psychiatric illness and not all had discontinued smoking. The role of Chantix in these reports is not known (see WARNINGS).

Get the Thursday-13 Code here.



Smoking Cessation Resources: Quick List

Here is a Quick List of Quit Smoking sites on the internet. This is by no means a complete list but some of my favorites that helped me along the way:

QuitNet
WhyQuit
American Cancer Society -Nationwide network of free local quit lines at 800-QUITNOW, questions answered by e-mail, message boards, brochures, other information on quitting smoking
American Lung Association -800-LUNG-USA-Freedom From Smoking online program, information about quitting smoking, facts about lung diseases and treatments, more
Chantix
Smokefree.gov
National Cancer Institute -877-44U-QUIT-Detailed information about tobacco and how to quit, surgeon general’s reports, live messaging service at Cancer.gov/Help
Nicotine-Anonymous.org -415-750-0328-List of local meetings in the United States and worldwide, publications in nine languages

Quit Meter
FREE >>> Download SilkQuit v2.60 for Microsoft Windows << FREE

…a New Beginning-Twelve Step Recovery Card w/envelope

…a New Beginning Originally uploaded by EMCphotos

Inside Verse: “Inside Verse: &quot;…Congratulations! May your days be full of ‘New Beginnings’.&quot;”

This is one of ten ‘Recovery’ Series Cards featuring my original fine art photos. Some of the cards will have a verse inside and some will be blank note cards. Visit my Etsy Shop to purchase this or other items!

Each note card features a 4×6 fine art photograph mounted on a 5×6.5 note card made from sturdy white cardstock. The 4×6 photos are professionally printed and white envelopes are included.

The Promises-Twelve Step Recovery Card w/Envelope

The Promises Originally uploaded by EMCphotos

Inside Verse: “…May all the promises come true in your life. Congratulations on your recovery!&quot; ” This is one of ten ‘Recovery’ Series Cards I am doing with my photos. Some of the cards will have a verse inside and some will be blank note cards. Visit my Etsy Shop to purchase this or other items!

Each note card features a 4×6 original fine art photograph mounted on a 5×6.5 note card made from sturdy white cardstock. The 4×6 photos are professionally printed and white envelopes are included.

Let Go and Let God-Recovery Card w/envelope

Let Go Originally uploaded by EMCphotos

Inside Verse: “…Remember, God doesn’t make junk!” This is one of ten ‘Recovery’ Series Cards I am doing with my photos. Some of the cards will have a verse inside and some will be blank note cards. Visit my Etsy Shop to purchase this or other items!

Each note card features a 4×6 original fine art photograph mounted on a 5×6.5 note card made from sturdy white cardstock. The 4×6 photos are professionally printed and white envelopes are included.

Chantix: R&D Chief MacKay’s Personal Opinion

Pfizer Research Chief’s Personal Take on Chantix
Posted by Scott Hensley
With questions about the safety of anti-smoking pill Chantix hurting sales, Pfizer’s head of R&D took to the opinion pages of the local paper in support of the medicine over the weekend.

Martin Mackay

Martin Mackay

Martin Mackay (pictured) wrote in the Day of New London, Conn., about his firsthand experience with the health toll of “cigarette addiction, having watched both of my parents smoke for most of their adult lives and my mother die of lung disease.”

His basic message was in keeping with points the company hit last week in a roundtable meeting with journalists. Quitting smoking is important, but hard. Chantix, despite some risks, remains a safe and effective option, in Pfizer’s view.

The drugmaker has upgraded the cautions on Chantix’s instructions to advise patients to stop taking Chantix in case of agitation, depression, or unusual behavior. Thoughts of suicide are a particular worry. A heightened concern about risk from Chantix led the FAA to ban the use of the drug by pilots and air-traffic controllers last month.

In his Chantix defense, Mackay couldn’t stop with data alone. He invoked some hometown pride in Chantix, one of Pfizer’s “homegrown” medicines.

The active ingredient in Chantix was invented by scientists in labs in Groton, Conn., on the eastern bank of the Thames River. On the opposite shore, in New London, other Pfizer workers designed and ran the clinical tests that led to the FDA’s approval of Chantix in May 2006. Pfizer employs 6,000 people in the area.

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After 5 Days-Back on the Chantix

Smoke Free 76 Days!

Wow! It seems like forever! I took Chantix for 6-weeks and thought I would try to get off of it because of bad things I am hearing in the news. I have not had any of the side effects-depression, suicidal thoughts, etc.-that they are discussing about Chantix. Anyway, I went off of it last Monday. It has a 5-day half life, sort of a self tapering system. So, by day 5, it is completely out of your system. Well, Thursday, day 4, I was kind of depressed and weepy,(which is exactly the way I am without my cigarettes.) Then Friday, I had a fully blown depression episode of crying and not being able to stop. That usually happens to me when I get off nicotine. When I would go to a lower dose nicotine patch is usually when I when get like that and smoke, hence I never got past 60 days before Chantix. When I am on Chantix I am fine, without it I could smoke just to make me quit crying. Anyway, I filled my Rx and got another six-week supply, (I only take one 1mg Chantix in the morning. I do not take two 1mg doses.) The one at night was just too much and I couldn’t get to sleep and when I finally did I didn’t want to get up. So one Chantix has been working for me for 6 weeks now.

So, I am back on the Chantix. Big deal! I did not smoke and I could of. There are plenty of people at work that would give me one. My son gave me a good idea on how to look at going back on the Chantix. He said, “Look at it like you do your anti-depressant. It is medicine, that helps you, not a drug.” Well, that helped me so much. As a matter of fact, my Doctor told me I could stay on it a year if that is what it takes for me not to smoke. I am not going to try and rush this thing.

It is a bigger risk to my life for me to smoke than it is to keep taking the Chantix.

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